GS-9973 | 2669

GS-9973 is a potent and highly selective Syk (spleen tyrosine kinase) inhibitor (IC₅₀ = 7.7 nM).

GS-9973 is a potent and highly selective Syk (spleen tyrosine kinase) inhibitor (IC₅₀ = 7.7 nM).

2669 | GS-9973 DataSheet

Alternate Name/Synonyms: 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine; Entospletinib

Appearance: Pale yellow solid

Formulation: N/A

CAS Number: 1229208-44-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₁N₇O

Molecular Weight: 411.5

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>50 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent Syk inhibitor

MDL Number: N/A

PubChem CID: 59473233

SMILES: C1COCCN1C2=CC=C(C=C2)NC3=NC(=CN4C3=NC=C4)C5=CC6=C(C=C5)C=NN6

InChi: InChI=1S/C23H21N7O/c1-2-17-14-25-28-20(17)13-16(1)21-15-30-8-7-24-23(30)22(27-21)26-18-3-5-19(6-4-18)29-9-11-31-12-10-29/h1-8,13-15H,9-12H2,(H,25,28)(H,26,27)

InChi Key: XSMSNFMDVXXHGJ-UHFFFAOYSA-N