GSK-0660 | 2897

GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively).

GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively).

2897 | GSK-0660 DataSheet

Alternate Name/Synonyms: 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylic acid methyl ester

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1014691-61-2

Structure Available?: yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₁₈N₂O₅S₂

Molecular Weight: 418.49

Cell-Permeable?: yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective PPARδ antagonist

MDL Number: MFCD12828770

PubChem CID: 46233311

SMILES: COC1=C(C=CC(=C1)NC2=CC=CC=C2)NS(=O)(=O)C3=C(SC=C3)C(=O)OC

InChi: InChI=1S/C19H18N2O5S2/c1-25-16-12-14(20-13-6-4-3-5-7-13)8-9-15(16)21-28(23,24)17-10-11-27-18(17)19(22)26-2/h3-12,20-21H,1-2H3

InChi Key: NDFKBGWLUHKMFY-UHFFFAOYSA-N