Description
GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively).
GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively).
Alternate Name/Synonyms: 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylic acid methyl ester
Appearance: Off-white solid
Formulation: N/A
CAS Number: 1014691-61-2
Structure Available?: yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₈N₂O₅S₂
Molecular Weight: 418.49
Cell-Permeable?: yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective PPARδ antagonist
MDL Number: MFCD12828770
PubChem CID: 46233311
SMILES: COC1=C(C=CC(=C1)NC2=CC=CC=C2)NS(=O)(=O)C3=C(SC=C3)C(=O)OC
InChi: InChI=1S/C19H18N2O5S2/c1-25-16-12-14(20-13-6-4-3-5-7-13)8-9-15(16)21-28(23,24)17-10-11-27-18(17)19(22)26-2/h3-12,20-21H,1-2H3
InChi Key: NDFKBGWLUHKMFY-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |