GSK-121 trifluoroacetate | B1034

GSK-121 is a novel protein arginine deiminase 4 (PAD4) inhibitor. GSK-121 was shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC₅₀ value of 3.2 µM.

GSK-121 is a novel protein arginine deiminase 4 (PAD4) inhibitor. GSK-121 was shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC₅₀ value of 3.2 µM.

B1034 | GSK-121 trifluoroacetate DataSheet

Alternate Name/Synonyms: (3-​amino-1-​piperidinyl)​[1-​methyl-​2-​(1-​methyl-​1H-​indol-​2-​yl)​-​1H-​benzimidazol-​5-​yl]​-methanone, 2,​2,​2-​trifluoroacetate

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1652591-80-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₅N₅O •CF₃COOH

Molecular Weight: 501.5

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (~30 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A novel protein arginine deiminase 4 (PAD4) inhibitor

MDL Number: N/A

PubChem CID: N/A

SMILES: O=C(N1CC(N)CCC1)C2=CC=C3N(C)C(C(N4C)=CC5=C4C=CC=C5)=NC3=C2.OC(C(F)(F)F)=O

InChi: InChI=1S/C23H25N5O.C2HF3O2/c1-26-19-8-4-3-6-15(19)13-21(26)22-25-18-12-16(9-10-20(18)27(22)2)23(29)28-11-5-7-17(24)14-28;3-2(4,5)1(6)7/h3-4,6,8-10,12-13,17H,5,7,11,14,24H2,1-2H3;(H,6,7)

InChi Key: CUCLWQZRCAQPJM-UHFFFAOYSA-N