Description
GSK-2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS (human Fatty Acid Synthase).
GSK-2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS (human Fatty Acid Synthase).
Alternate Name/Synonyms: 4-[4-(benzofuran-5-yl)phenyl]-3-[[(3S)-1-(cyclopropanecarbonyl)pyrrolidin-3-yl]methyl]-1H-1,2,4-triazol-5-one;2-(hydroxymethyl)-2-(methoxymethyl)quinuclidin-3-one
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1332331-21-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₅H₂₄N₄O₃
Molecular Weight: 428.48
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent human Fatty Acid Synthase (FAS) inhibitor
MDL Number: N/A
PubChem CID: 67376285
SMILES: C1CC1C(=O)N2CCC(C2)CC3=NNC(=O)N3C4=CC=C(C=C4)C5=CC6=C(C=C5)OC=C6
InChi: InChI=1S/C25H24N4O3/c30-24(18-1-2-18)28-11-9-16(15-28)13-23-26-27-25(31)29(23)21-6-3-17(4-7-
InChi Key: AQTPWCUIYUOEMG-INIZCTEOSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |