26
GSK-LSD1 dihydrochloride | B1258
- SKU:
- 26-B1258-GEN
- Availability:
- Usually shipped in 5 working days
Description
GSK-LSD1 is a potent and selective inhibitor of lysine specific demethylase 1 (LSD1). GSK-LSD1 2HCl irreversibly inhibits LSD1 with IC₅₀ value of 16 nM and is > 1000 fold selective over LSD2, MAO-A and MAO-B, which were related to FAD utilizing enzymes. GSK-LSD1 potently inhibits proliferation of varies cancer cell lines by changing gene expression patterns.
GSK-LSD1 is a potent and selective inhibitor of lysine specific demethylase 1 (LSD1). GSK-LSD1 2HCl irreversibly inhibits LSD1 with IC₅₀ value of 16 nM and is > 1000 fold selective over LSD2, MAO-A and MAO-B, which were related to FAD utilizing enzymes. GSK-LSD1 potently inhibits proliferation of varies cancer cell lines by changing gene expression patterns.
B1258 | GSK-LSD1 dihydrochloride DataSheet
Alternate Name/Synonyms: N-((1R,2S)-2-phenylcyclopropyl)piperidin-4-amine dihydrochloride
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 1431368-48-7 (free base)
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C14H22Cl2N2
Molecular Weight: 289.24
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: H₂O (>20 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A potent and selective lysine specific demethylase 1 (LSD1)inhibitor
MDL Number: N/A
PubChem CID: 71522234
SMILES: C1CNCCC1NC2CC2C3=CC=CC=C3
InChi: InChI=1S/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/m0/s1
InChi Key: BASFYRLYJAZPPL-UONOGXRCSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |