Description
A potent, second generation HIV integrase inhibitor (IC₅₀ = 2.7 nM) that displays potent antiviral activity.
GSK1349572 is a potent, second generation HIV integrase inhibitor (IC₅₀ = 2.7 nM) that displays potent antiviral activity.
Alternate Name/Synonyms: 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1051375-16-6
Structure Available?: Yes
Peptide sequence: No
Salt Form: No
Molecular Formula: C₂₀H₁₉F₂N₃O₅
Molecular Weight: 419.38
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>80 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A potent HIV integrase inhibitor
MDL Number: N/A
PubChem CID: 54726191
SMILES: CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
InChi: InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1
InChi Key: RHWKPHLQXYSBKR-BMIGLBTASA-N
Additional Information
Storage Condition: |
-20 ̊C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |