Gsk3b Antibody| F44221-0.08ML/F44221-0.4ML

Gsk3b Antibody| F44221-0.08ML/F44221-0.4ML | Gentaur UK, US & Europe Distribution

Background: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Mouse

Predicted Spacies Reactivity: Human, Rat

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the Gsk3b antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Gsk3b antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 30-59 from the mouse protein was used as the immunogen for this Gsk3b antibody.

Storage: Aliquot the Gsk3b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A