BMP1 Antibody| F45359-0.08ML/F45359-0.4ML

BMP1 Antibody| F45359-0.08ML/F45359-0.4ML | Gentaur UK, US & Europe Distribution

Background: The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Mouse

Predicted Spacies Reactivity: N/A

Application: IHC, WB, ELISA

Application Details: IHC (Paraffin): 1:50-1:100, Western blot: 1:1000

Application Note: Titration of the BMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This BMP1 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 957-986 from the human protein was used as the immunogen for this BMP1 antibody.

Storage: Aliquot the BMP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A