LOX Antibody| F40401-0.08ML/F40401-0.4ML/F53728-0.1ML

LOX Antibody| F40401-0.08ML/F40401-0.4ML/F53728-0.1ML | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Format: Purified

Clone: 624CT23.7.3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG2b

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Rat, Pig

Application: WB, ELISA

Application Details: Western blot: 1:100-1:500

Application Note: Titration of the LOX antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This LOX antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 234-260 from the human protein was used as the immunogen for this LOX antibody.

Storage: Aliquot the LOX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A