GSN Antibody (N-term) [AMM22124G]

GSN Antibody (N-term) [AMM22124G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This GSN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the N-terminal region of human GSN.

Cellular Localisation: [Isoform 2]: Cytoplasm, cytoskeleton.

Molecular Weight: 85698

Clone: Monoclonal

Gene Name: GSN

Gene ID: 2934

Function: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping) . It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.

Summary: Tissue Location: Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells

Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:500~1000

Synonyms: Gelsolin, AGEL, Actin-depolymerizing factor, ADF, Brevin, GSN