GSTA1 Antibody (ascites) [AMM05230G]

GSTA1 Antibody (ascites) [AMM05230G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: M

Specificity: This GSTA1 monoclonal antibody is generated from mouse immunized with GSTA1 recombinant protein.

Cellular Localisation: Cytoplasm.

Molecular Weight: 25631

Clone: Monoclonal

Gene Name: GSTA1

Gene ID: 2938

Function: Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable) . Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911) . It also catalyzes the isomerization of D5-androstene-3, 17-dione (AD) into D4-androstene- 3, 17-dione and may therefore play an important role in hormone biosynthesis (PubMed:11152686) . Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S) - hydroperoxy- (9Z, 11E) -octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid (PubMed:16624487) .

Summary: Tissue Location: Liver.

Form: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000~32000

Synonyms: Glutathione S-transferase A1, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, Glutathione S-transferase A1, N-terminally processed, GSTA1