GTF3C4 monoclonal Antibody | MB63476

GTF3C4 monoclonal Antibody | MB63476 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:500

Background: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. [UniProtKB/Swiss-Prot Function]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: general transcription factor IIIC subunit 4

Molecular Weight: 91.9 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: KAT12; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA

Immunogen: Human recombinant protein fragment corresponding to amino acids 583-822 of human GTF3C4 (NP_036336) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A