GTPBP5 polyclonal Antibody | BS61198

GTPBP5 polyclonal Antibody | BS61198 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Small G proteins act as molecular switches for regulation of variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. GTPBP5 (GTP-binding protein 5), also known as OBGH1, is a 406 amino acid small G protein that contains an amino-terminal mitochondria-localization signal. Knockdown of GTPBP5 mRNA results in abnormal nuclear morphologies and elongated mitochondria. In vitro studies demonstrate that GTPBP5 exhibits GTPase activity, cycling between an active GTP-bound state and an inactive GDP-bound state. Activation of GTPases usually results in rearrangements of filamentous actin and the formation of actin stress fibers.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GTPBP5 polyclonal Antibody detects endogenous levels of GTPBP5 protein.

Molecular Weight: ~ 44 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Mitochondrial ribosome-associated GTPase 2; GTP-binding protein 5; Protein obg homolog 1; ObgH1; MTG2; GTPBP5; OBGH1

Immunogen: A synthetic peptide corresponding to residues in Human GTPBP5.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: