GW-786034 | 1916

Cell-permeable. A potent and selective multi-targeted tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor and c-kit, key proteins responsible for tumor growth and angiogenesis.

GW-786034 is a potent and selective multi-targeted tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor and c-kit, key proteins responsible for tumor growth and angiogenesis.

1916 | GW-786034 DataSheet

Alternate Name/Synonyms:

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 444731-52-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₃N₇O₂S

Molecular Weight: 437.52

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 8 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A potent and selective multi-targeted tyrosine kinase inhibitor

MDL Number: MFCD11616589

PubChem CID: 10113978

SMILES: CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N

InChi: InChI=1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22, 29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5- 12H,1-4H3,(H2,22,29,30)(H,23,24,25)

InChi Key: CUIHSIWYWATEQL-UHFFFAOYSA-N