GW1929 | 2057

A potent (<10 nM) and subtype-selective (>1000-fold) peroxisome proliferator-activated receptor (PPAR)γ agonist. Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo.

GW1929 is a potent (<10 nM) and subtype-selective (>1000-fold) peroxisome proliferator-activated receptor (PPAR)γ agonist. Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo.

2057 | GW1929 DataSheet

Alternate Name/Synonyms: N-(2-Benzoylphenyl)-L-tyrosine PPARγ Agonist; (2S)-((2-Benzoylphenyl)amino-3-[4-[2-(methylpyridin-2-ylamino)ethoxy]phenyl]propionic acid

Appearance: Off-white to yellow solid

Formulation: N/A

CAS Number: 196808-24-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₀H₂₉N₃O₄

Molecular Weight: 495.57

Cell-Permeable?: No

Purity: ≥98% by NMR

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent PPARγ agonist

MDL Number: N/A

PubChem CID: 6518171

SMILES: CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4

InChi: InChI=1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17- 24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18,27, 32H,19-21H2,1H3,(H,35,36)/t27-/m0/s1

InChi Key: QTQMRBZOBKYXCG-MHZLTWQESA-N