GZMA Antibody | 22-069

GZMA Antibody | 22-069 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-262 of human GZMA (NP_006135.1) .

Research Area: Apoptosis, Cell Cycle, Immunology, Innate Immunity

Tested Application: WB, IF

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: Mouse spleen

Positive Control 2: Mouse thymus

Positive Control 3: Rat intestine

Positive Control 4: Rat spleen

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 35kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: GZMA, granzyme A, Hanukah factor serine protease) , Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3, CTL tryptase, HFSP, CTLA3, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) , GZMA

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.