H1FNT Antibody (N-Term) [ApR04922G]

H1FNT Antibody (N-Term) [ApR04922G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This H1FNT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 59-93 amino acids from human H1FNT.

Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:Q8CJI4}. Chromosome {ECO:0000250|UniProtKB:Q8CJI4}. Note=In round and elongating spermatids, specifically localizes to a chromatin domain at the apical pole. {ECO:0000250|UniProtKB:Q8CJI4}

Molecular Weight: 28116

Clone: Polyclonal

Gene Name: H1-7 (HGNC:24893)

Gene ID: 341567

Function: Essential for normal spermatogenesis and male fertility (PubMed:16533358) . Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single- stranded DNA, ATP and protamine-1.

Summary: Tissue Location: Testis-specific..

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Testis-specific H1 histone, Haploid germ cell-specific nuclear protein 1, Histone H1t2, H1FNT, HANP1