LBD
HAND1 Antibody (N-term) [AMM08775G]
- SKU:
- LBD-AMM08775G
- Availability:
- Usually ships in 5 working days
Description
HAND1 Antibody (N-term) [AMM08775G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: Rat
Specificity: This HAND1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 83-116 amino acids from the N-terminal region of human HAND1.
Cellular Localisation: Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity (By similarity) .
Molecular Weight: 23627
Clone: Polyclonal
Gene Name: HAND1
Gene ID: 9421
Function: Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis (By similarity) . Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity) . Acts as a transcriptional repressor of SOX15 (By similarity) . In the adult, could be required for ongoing expression of cardiac-specific genes (PubMed:9931445) .
Summary: Tissue Location: Heart.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Heart- and neural crest derivatives-expressed protein 1, Class A basic helix-loop-helix protein 27, bHLHa27, Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1, eHAND, HAND1, BHLHA27, EHAND