HAND1 monoclonal Antibody | MB63487

HAND1 monoclonal Antibody | MB63487 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: FC, IF, WB

Application Range: WB 1:500, IF 1:100, FLOW 1:100

Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: heart and neural crest derivatives expressed 1

Molecular Weight: 23.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: bHLHa27; eHand; Hxt; Thing1

Immunogen: Full length human recombinant protein of human HAND1 (NP_004812) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A