Description
Harzianum A is a trichothecene fungal metabolite isolated from T. harzianum. It is cytotoxic to HeLa, MCF-7, and HT-1080 cells (IC50s = 5.07, 10.13, and 0.65 μg/ml, respectively) and displays antifungal activity.
Harzianum A is a trichothecene fungal metabolite isolated from T. harzianum. It is cytotoxic to HeLa, MCF-7, and HT-1080 cells (IC50s = 5.07, 10.13, and 0.65 μg/ml, respectively) and displays antifungal activity.
Alternate Name/Synonyms: (2E,4E,6Z)-8-oxo-8-[(1S,2R,7R,9R,11R,12S)-1,2,5-trimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-11-yl]oxyocta-2,4,6-trienoic acid
Appearance: Off-white solid
Formulation:
CAS Number: 156250-74-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₂₈O₆
Molecular Weight: 400.4
Cell-Permeable?: TRUE
Purity: ≥95%
Solubilities: DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A trichothecene fungal metabolite
MDL Number:
PubChem CID: 6444304
SMILES: CC1=C[C@]2([H])[C@](C3(C)C4(OC4)[C@](C[C@H]3OC(/C=C\C=C\C=C\C(O)=O)=O)([H])O2)(C)CC1
InChi: InChI=1S/C23H28O6/c1-15-10-11-21(2)16(12-15)28-18-13-17(22(21,3)23(18)14-27-23)29-20(26)9-7-5-4-6-8-19(24)25/h4-9,12,16-18H,10-11,13-14H2,1-3H3,(H,24,25)/b5-4+,8-6+,9-7-/t16-,17-,18-,21+,22?,23?/m1/s1
InChi Key: FVRDNLIUSWSBCT-WNNZSMTESA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |