HBA1 polyclonal Antibody | BS90612

HBA1 polyclonal Antibody | BS90612 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC IP

Application Range: WB:1:1,000 IHC:1:10-1:50

Background: Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme) . The α (16p13.3; 5'-ζ-pseudoz-pseudo α2-pseudo α1-α2-α1-?1-3') and β (11p15.5) globin loci determine the basic hemoglobin structure. The globin portion of hemoglobin consists of two α chains and two β chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between α and β chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the α1-β2 cleavage plane. When the two α1-β2 interfaces are closely bound, hemoglobin has a low affinity for oxygen. Hb A, which contains two α chains plus two β chains, comprises 97% of total circulating hemoglobin. The remaining 3% of total circulating hemoglobin is comprised of Hb A-2, which consists of two α chains plus two δ chains, and fetal hemoglobin (Hb F), which consists of two α chains together with two γ chains.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: HBA1 polyclonal Antibody detects endogenous levels of HBA1 protein.

Molecular Weight: 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HBA1, HBA2, Alpha 1 globin, Alpha globin, Alpha one globin, Alpha-globin, HBA, HBA1, HBA2, Hemoglobin alpha 1, Hemoglobin alpha 1 chain, Hemoglobin alpha 1 globin chain, Hemoglobin alpha 2, Hemoglobin alpha chain, Hemoglobin subunit alpha, MGC126895, MGC126897,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: