Description
HBG1/HBG2 Polyclonal Antibody | E-AB-18774 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: A gamma globin, G gamma globin, Gamma 1 globin, Gamma 2 globin, Gamma A hemoglobin, Gamma globin, Hb F Agamma, Hb F Ggamma, hbfagamma, hbfggamma, HBG 1, HBG 2, HBG1, HBG2, HBGA, HBGR, Hemoglobin gamma 1 chain , Hemoglobin gamma 2 chain , Hemoglobin gamma A, Hemoglobin gamma A chain , Hemoglobin gamma G, Hemoglobin gamma G chain , Hemoglobin gamma regulator of, Hemoglobin subunit gamma 1, Hemoglobin subunit gamma 2, HSGGL 1, HSGGL1, Methemoglobin, PRO 2979, PRO2979
Application: WB, IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cardiovascular
Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human HBG1/HBG2
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 16 kDa
Molecular Weight(Observed): Refer to figures