HDAC1&2 Inhibitor | B2930

HDAC1&2 inhibitor selectively inhibits Histone deacetylases HDAC1 and HDAC2 with an IC₅₀ of 10 nM and 105 nM for HDAC1 and HDAC2 respectively. It shows a GI₅₀ of 100 nM for HCT-116 cells.

HDAC1&2 inhibitor selectively inhibits Histone deacetylases HDAC1 and HDAC2 with an IC₅₀ of 10 nM and 105 nM for HDAC1 and HDAC2 respectively. It shows a GI₅₀ of 100 nM for HCT-116 cells.

B2930 | HDAC1&2 Inhibitor DataSheet

Alternate Name/Synonyms: Methyl ester of N-[[4-[[[2-amino-5-(2-thienyl)phenyl]amino]carbonyl]phenyl]methyl]-carbamic acid; methyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate

Appearance: Solid

Formulation:

CAS Number: 1013330-84-1

Structure Available?: True

Peptide sequence:

Salt Form: false

Molecular Formula: C₂₀H₁₉N₃O₃S

Molecular Weight: 381.45

Cell-Permeable?: True

Purity: 97%

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A selective inhibitor of HDAC1 and 2

MDL Number:

PubChem CID: 44447194

SMILES: COC(=O)NCC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=CS3)N

InChi: InChI=1S/C20H19N3O3S/c1-26-20(25)22-12-13-4-6-14(7-5-13)19(24)23-17-11-15(8-9-16(17)21)18-3-2-10-27-18/h2-11H,12,21H2,1H3,(H,22,25)(H,23,24)

InChi Key: XPYFYVJCMDDGKF-UHFFFAOYSA-N