HDAC11 Antibody (N-term) [AMM08591G]

HDAC11 Antibody (N-term) [AMM08591G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC11.

Cellular Localisation: Nucleus. Note=Predominantly nuclear.

Molecular Weight: 39183

Clone: Polyclonal

Gene Name: HDAC11

Gene ID: 79885

Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Summary: Tissue Location: Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Histone deacetylase 11, HD11, HDAC11