Description
HDAC3 is a member of the class I mammalian histone deacetylase family, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC3 is composed of 428 amino acid residues. HDAC3 interacts with a growing number of transcriptional factors including SMRT and N-CoR. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.
3603 | HDAC3 Antibody DataSheet
Antibody Target: HDAC3
Target Alternative Name: SMAP45 , HD3 , RPD3 , RPD3-2
Tag Line:
Category: HDAC
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse, rat, chicken
Immunogen Sequence: Synthetic peptide corresponding to the C-terminus of human HDAC-3
Accession #: NP_003874
Gene ID: 8841
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.2 mg/ml
Formulation: 100 µg (0.2 mg/ml) peptide affinity purified rabbit anti-HDAC3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification: Affinity purified
Application: Western blot, Immunohistochemistry
Positive Control:
Application And Usages: Western blotting (0.5-4 µg/ml)and Immunohistochemistry (20-30 µg/ml). However, the optimal conditions should be determined individually.The antibody detects the 49 kDa HDAC3. It does not cross-react with other HDAC proteins including HDAC1, 2, 4, 5, 6, 7, and 8. Jurkat cell lysate (Cat.# 2401-100) can be used as a positive control.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |