Description
HDAC4 Polyclonal Antibody | E-AB-31646 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: AHO3, BDMR, EC 3.5.1.98, HA6116, HD 4, HD4, HDAC 4, HDAC A, HDAC4, HDAC4, HDACA, Histone deacetylase 4, Histone Deacetylase A, KIAA0288
Application: WB, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells
Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from human HDAC4 around the non-phosphorylation site of Ser632.
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, ELISA 1:20000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 119 kDa
Molecular Weight(Observed): 119 kDa