HDAC6 Antibody | 7901

HDAC6 Antibody | 7901 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: HDAC6 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human HDAC6.
The immunogen is located within the last 50 amino acids of HDAC6.

Research Area: Neuroscience

Tested Application: E, WB, IHC-P, IF

Application: HDAC6 body can be used for detection of HDAC6 by Western blot at 0.5 - 1 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: HDAC6 antibody is human and mouse reactive. Multiple isoforms of HDAC6 are known to exist. HDAC6 antibody is predicted to not cross-react with other members of the HDAC family.

Positive Control 1: Cat. No. 1313 - Human Testis Tissue Lysate

Positive Control 2: Cat. No. 11-701 - Human Testis Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 55 kDa
Observed: 32 kDa

Validation: N/A

Isoform: N/A

Purification: HDAC6 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: HDAC6 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: HDAC6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: HDAC6 Antibody: HD6, JM21, CPBHM, KIAA0901, Histone deacetylase 6, HD6

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class II of the HDAC family comprises six members, HDAC4, 5, 6, 7, 9 and 10, each of which appear to have tissue-specific roles (1) . HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other (2) . HDAC6 has been shown to be part of the microtubule network and acts as a specific alpha-tubulin deacetylase, and has been suggested to be a potential therapeutic target in neurodegenerative disease (3) .