HDM Inhibitor, 2,4-PDCA | 2304

A histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1 proteins with an IC₅₀ values of 4.3 µM for JARID1B and 4.1 µM for JARID1A. 2, 4-PDCA does not inhibit UTX even at 10 µM.

A histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1 proteins with an IC₅₀ values of 4.3 µM for JARID1B and 4.1 µM for JARID1A.

2304 | HDM Inhibitor, 2,4-PDCA DataSheet

Alternate Name/Synonyms: 2,4-Pyridinecarboxylic acid, monohydrate

Appearance: White solid

Formulation: N/A

CAS Number: 207671-42-9

Structure Available?: Yes

Peptide sequence: No

Salt Form: No

Molecular Formula: C₇H₅N₄ .H₂O

Molecular Weight: 185.13

Cell-Permeable?: Yes

Purity: ≥98% by titration

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A histone lysine demethylase (HKDM) inhibitor

MDL Number: MFCD00149413

PubChem CID: 10365

SMILES: C1=CN=C(C=C1C(=O)O)C(=O)O

InChi: InChI=1S/C7H5NO4/c9-6(10)4-1-2-8-5(3-4)7(11)12/h1-3H,(H,9,10)(H,11,12)

InChi Key: MJIVRKPEXXHNJT-UHFFFAOYSA-N