HEPACAM2 Antibody | 7111

HEPACAM2 Antibody | 7111 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (95%)

Immunogen: Rabbit polyclonal HEPACAM2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human HEPACAM2.
The immunogen is located within amino acids 370 - 420 of HEPACAM2.

Research Area: Cancer, Cell Cycle

Tested Application: E, WB

Application: HEPACAM2 antibody can be used for detection of HEPACAM2 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Specificiy: HEPACAM2 antibody is human, mouse and rat reactive. At least two isoforms of HEPACAM2 are known to exist; this antibody will detect both isoforms. HEPACAM2 antibody is predicted to not cross-react with HEPACAM.

Positive Control 1: Cat. No. 1403 - Mouse Brain Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 51 kDa

Validation: N/A

Isoform: N/A

Purification: HEPACAM2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: HEPACAM2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: HEPACAM2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: HEPACAM2 Antibody: MIKI, MIKI, UNQ305/PRO346, HEPACAM family member 2, Mitotic kinetics regulator

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: HEPACAM2 Antibody: HEPACAM2 (Hepatocyte cell adhesion molecule 2) , a type I N-linked transmembrane glycoprotein, belongs to the immunoglobulin superfamily. The exact function of HEPACAM2 is currently unknown, but the related protein HEPACAM forms cishomodimers on the cell surface to regulate the cell adhesion and may inhibit cell growth through suppression of cell proliferation. HEPACAM and HEPACAM2 mRNA are differentially regulated in canine tumors, with HEPACAM2 mRNA showing increased levels in adenomas, but decreased levels in metastatic carcinomas compared to normal tissues, while HEPACAM protein levels decreased in adenomas. It is therefore likely that HEPACAM2 plays a different role than HEPACAM in the development and progression to tumors.