HERC4 Antibody (Center) [APR33123G]

HERC4 Antibody (Center) [APR33123G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This HERC4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 445-479 amino acids from the Central region of human HERC4.

Cellular Localisation: Cytoplasm, cytosol. Note=shows a punctate cytoplasmic distribution

Molecular Weight: 118563

Clone: Polyclonal

Gene Name: HERC4

Gene ID: 26091

Function: Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.

Summary: Tissue Location: Expressed in brain and testis and detected in heart and placenta.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Probable E3 ubiquitin-protein ligase HERC4, 632-, HECT domain and RCC1-like domain-containing protein 4, HERC4, KIAA1593