Hesperetin | B3239

Hesperetin is a naturally occurring flavonoid that displays diverse biological activities. It inhibits neuroinflammation on microglia by suppressing inflammatory cytokines and MAPK pathways. It reduces ApoB protein levels, ACAT2 expression, and LDL degradation in HepG2 cells when used at concentrations ranging from 10 to 200 µM. Hesperetin also acts as a potent and broad-spectrum inhibitor against human UGT activity.

Hesperetin is a naturally occurring flavonoid that displays diverse biological activities. It inhibits neuroinflammation on microglia by suppressing inflammatory cytokines and MAPK pathways. It reduces ApoB protein levels, ACAT2 expression, and LDL degradation in HepG2 cells when used at concentrations ranging from 10 to 200 µM. Hesperetin also acts as a potent and broad-spectrum inhibitor against human UGT activity.

B3239 | Hesperetin DataSheet

Alternate Name/Synonyms: (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one

Appearance: White to pale yellow or light brown powder

Formulation:

CAS Number: 520-33-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₄O₆

Molecular Weight: 302.28

Cell-Permeable?: True

Purity: ≥95%

Solubilities: >25 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A naturally occurring flavonoid that displays diverse biological activities

MDL Number: MFCD00075646

PubChem CID: 72281

SMILES: COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)O

InChi: InChI=1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3/t14-/m0/s1

InChi Key: AIONOLUJZLIMTK-AWEZNQCLSA-N