HEXIM2 Antibody (C-Term) [APR33443G]

HEXIM2 Antibody (C-Term) [APR33443G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This HEXIM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 235-269 amino acids from of human HEXIM2.

Cellular Localisation: Nucleus.

Molecular Weight: 32419

Clone: Polyclonal

Gene Name: HEXIM2

Gene ID: 124790

Function: Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor (PubMed:15713661, PubMed:15713662) . Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed:15713661, PubMed:15713662) .

Summary: Tissue Location: Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:8000

Synonyms: Protein HEXIM2, Hexamethylene bis-acetamide-inducible protein 2, HEXIM2