LBD
HFE2 Antibody (Center) [AMM05342G]
- SKU:
- LBD-AMM05342G
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Description
HFE2 Antibody (Center) [AMM05342G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This HFE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-162 amino acids from the Central region of human HFE2.
Cellular Localisation: Cell membrane; Lipid-anchor, GPI- anchor. Note=Also released in the extracellular space
Molecular Weight: 45080
Clone: Polyclonal
Gene Name: HJV (HGNC:4887)
Gene ID: 148738
Function: Acts as a bone morphogenetic protein (BMP) coreceptor (PubMed:18976966) . Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis (PubMed:18976966) .
Summary: Tissue Location: Adult and fetal liver, heart, and skeletal muscle.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, WB
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Hemojuvelin, Hemochromatosis type 2 protein, RGM domain family member C, HFE2, HJV, RGMC