HFE2 Antibody (Center) [AMM05342G]

HFE2 Antibody (Center) [AMM05342G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This HFE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-162 amino acids from the Central region of human HFE2.

Cellular Localisation: Cell membrane; Lipid-anchor, GPI- anchor. Note=Also released in the extracellular space

Molecular Weight: 45080

Clone: Polyclonal

Gene Name: HJV (HGNC:4887)

Gene ID: 148738

Function: Acts as a bone morphogenetic protein (BMP) coreceptor (PubMed:18976966) . Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis (PubMed:18976966) .

Summary: Tissue Location: Adult and fetal liver, heart, and skeletal muscle.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Hemojuvelin, Hemochromatosis type 2 protein, RGM domain family member C, HFE2, HJV, RGMC