Hh-Ag1.5 | B2160

Hh-Ag 1.5 is a potent and selective agonist of the Hh pathway (Smoothened/Smo agonist) (EC₅₀ = 1 nM).

Hh-Ag 1.5 is a potent and selective agonist of the Hh pathway (Smoothened/Smo agonist) (EC₅₀ = 1 nM).

B2160 | Hh-Ag1.5 DataSheet

Alternate Name/Synonyms: 3-chloro-4,7-difluoro-N-(4-(methylamino)cyclohexyl)-N-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide

Appearance: Yellow solid

Formulation: N/A

CAS Number: 612542-14-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₂₆N₃OS

Molecular Weight: 526.04

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A Hedgehog (Hh) pathway agonist

MDL Number: N/A

PubChem CID: N/A

SMILES: CN[C@@H]1CC[C@H](CC1)N(Cc2cccc(c2)c3ccncc3)C(=O)c5sc4c(F)ccc(F)c4c5Cl

InChi: InChI=1S/C28H26ClF2N3OS/c1-32-20-5-7-21(8-6-20)34(16-17-3-2-4-19(15-17)18-11-13-33-14-12-18)28(35)27-25(29)24-22(30)9-10-23(31)26(24)36-27/h2-4,9-15,20-21,32H,5-8,16H2,1H3/t20-,21-

InChi Key: RXZDWPYJFCAZCW-MEMLXQNLSA-N