Hh Signaling Pathway Antagonist | 1659

Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC₅₀ = 70 nM).

Hh Signaling Pathway Antagonist is a potent antagonist of the Hedgehog (Hh) signaling pathway (IC₅₀ = 70 nM).

1659 | Hh Signaling Pathway Antagonist DataSheet

Alternate Name/Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 330796-24-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₁₅ClF₄N₄O₂

Molecular Weight: 490.84

Cell-Permeable?: Yes

Purity: ≥97% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A hedgehog (Hh) signaling pathway inhibitor

MDL Number: N/A

PubChem CID: 9913498

SMILES: C1=CC=C2C(=C1)C(=O)N(C(=N2)CNC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C4=CC=C(C=C4)F

InChi: InChI=1S/C23H15ClF4N4O2/c24-18-10-7-14(11-17(18)23(26, 27)28)30-22(34)29-12-20-31-19-4-2-1-3-16(19)21(33)32(20)15-8-5-13(25)6- 9-15/h1-11H,12H2,(H2,29,30,34)

InChi Key: NYOXUHUPXGFHIB-UHFFFAOYSA-N