Histone H1.0 Antibody | 22-554

Histone H1.0 Antibody | 22-554 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human H1F0 (NP_005309.1) .

Research Area: Other

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:2000
IHC: 1:100 - 1:200
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: MCF7

Positive Control 2: HepG2

Positive Control 3: Jurkat

Positive Control 4: HeLa

Positive Control 5: 293T

Positive Control 6: N/A

Molecular Weight: Observed: 36kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: H1F0, H10, H1FV, MGC5241

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family.