Histone H3 (Acetyl-K123) polyclonal Antibody | BS64086

Histone H3 (Acetyl-K123) polyclonal Antibody | BS64086 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Chromatin is the arrangement of DNA and proteins in which chromosomes are formed. Correspondingly, chromatin is formed from nucleosomes, which are comprised of a set of four histone proteins (H2A, H2B, H3, H4) wrapped with DNA. Chromatin is a very dynamic structure in which numerous post-translational modifications work together to activate or repress the availability of DNA to be copied, transcribed, or repaired. These marks decide which DNA will be open and commonly active (euchromatin) or tightly wound to prevent access and activation (heterochromatin) . Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Ac-Histone H3 (K123) polyclonal Antibody detects endogenous levels of Histone H3 protein only when acetylated at Lys123.

Molecular Weight: ~ 14 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Histone H3.1; Histone H3A; H3FA; Histone H3B; H3FL; Histone H3C; H3FC; Histone H3D; H3FB; Histone H3E; H3FD; Histone H3F; H3FI; Histone H3G; H3FH; Histone H3H; H3FK; Histone H3I; H3FF; Histone H3J; H3FJ; Histone H3.2; Histone H3/m; Histone H3/o; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3

Immunogen: Synthetic peptide derived from human Histone H3 around the acetylated at Lys123.

Conjugate: Unconjugated

Modification: Acetylated

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .

Pathway: