HMMR Antibody (C-term) [APR03616G]

HMMR Antibody (C-term) [APR03616G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This HMMR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-697 amino acids from the C-terminal region of human HMMR.

Cellular Localisation: Cell surface {ECO:0000250|UniProtKB:Q00547}. Cytoplasm {ECO:0000250|UniProtKB:Q00547}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q00547}

Molecular Weight: 84100

Clone: Polyclonal

Gene Name: HMMR

Gene ID: 3161

Function: Receptor for hyaluronic acid (HA) (By similarity) . Involved in cell motility (By similarity) . When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity) .

Summary: Tissue Location: Expressed in testis (PubMed:22965910) . Expressed in the breast (PubMed:8890751) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000

Synonyms: Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168, HMMR, IHABP, RHAMM