HMN-214 | B1646

HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM.

HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM.

B1646 | HMN-214 DataSheet

Alternate Name/Synonyms: HMN-214; HMN214; HMN 214; (E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide; IVX214; IVX 214; IVX-214; N-(4-methoxyphenyl)sulfonyl-N-[2-[(E)-2-(1-oxidopyridin-1-ium-4-yl)ethenyl]phenyl]acetamide

Appearance: Solid

Formulation: N/A

CAS Number: 173529-46-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₀N₂O₅S

Molecular Weight: 424.47

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent PLK1 inhibitor

MDL Number: MFCD12756255

PubChem CID: 9888590

SMILES: CC(=O)N(C1=CC=CC=C1C=CC2=CC=[N+](C=C2)[O-])S(=O)(=O)C3=CC=C(C=C3)OC

InChi: InChI=1S/C22H20N2O5S/c1-17(25)24(30(27,28)21-11-9-20(29-2)10-12-21)22-6-4-3-5-19(22)8-7-18-13-15-23(26)16-14-18/h3-16H,1-2H3/b8-7+

InChi Key: OCKHRKSTDPOHEN-BQYQJAHWSA-N