Description
HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM.
HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM.
Alternate Name/Synonyms: HMN-214; HMN214; HMN 214; (E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide; IVX214; IVX 214; IVX-214; N-(4-methoxyphenyl)sulfonyl-N-[2-[(E)-2-(1-oxidopyridin-1-ium-4-yl)ethenyl]phenyl]acetamide
Appearance: Solid
Formulation: N/A
CAS Number: 173529-46-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₂₀N₂O₅S
Molecular Weight: 424.47
Cell-Permeable?: Yes
Purity: >98%
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent PLK1 inhibitor
MDL Number: MFCD12756255
PubChem CID: 9888590
SMILES: CC(=O)N(C1=CC=CC=C1C=CC2=CC=[N+](C=C2)[O-])S(=O)(=O)C3=CC=C(C=C3)OC
InChi: InChI=1S/C22H20N2O5S/c1-17(25)24(30(27,28)21-11-9-20(29-2)10-12-21)22-6-4-3-5-19(22)8-7-18-13-15-23(26)16-14-18/h3-16H,1-2H3/b8-7+
InChi Key: OCKHRKSTDPOHEN-BQYQJAHWSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |