HMOX1 Antibody (Center) [APR30751G]

HMOX1 Antibody (Center) [APR30751G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This HMOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-204 amino acids from the Central region of human HMOX1.

Cellular Localisation: Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side

Molecular Weight: 32819

Clone: Polyclonal

Gene Name: HMOX1

Gene ID: 3162

Function: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.

Summary: Tissue Location: Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Heme oxygenase 1, HO-1, HMOX1, HO, HO1