HNF1AAntibody (Ascites) [AMM22140G]

HNF1AAntibody (Ascites) [AMM22140G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This HNF1A antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 177-205 amino acids from human HNF1A .

Cellular Localisation: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:10966642}

Molecular Weight: 67356

Clone: Monoclonal

Gene Name: HNF1A

Gene ID: 6927

Function: Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity) . Binds to the inverted palindrome 5'- GTTAATNATTAAC-3' (PubMed:12453420, PubMed:10966642) . Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity) .

Summary: Tissue Location: Liver.

Form: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:100~1600

Synonyms: Hepatocyte nuclear factor 1-alpha, HNF-1-alpha, HNF-1A, Liver-specific transcription factor LF-B1, LFB1, Transcription factor 1, TCF-1, HNF1A, TCF1