Honokiol | 1762

Present as an active principle in the plant Magnolia grandiflora. Displays anxiolytic, antithrombotic, anti-tumor properties, etc. modulates the NF-κB activation pathway, an upstream effector VEGF, COX-2, and MCL1, all significant pro-angiogenic and survival factors. Honokiol induces caspase-dependent apoptosis in a TRAIL-mediated manner, and potentiates the pro-apoptotic effects of doxorubicin and other etoposides.

Honokiol is present as an active principle in the plant Magnolia grandiflora. Displays anxiolytic, antithrombotic, anti-tumor properties, etc. modulates the NF-κB activation pathway, an upstream effector VEGF, COX-2, and MCL1, all significant pro-angiogenic and survival factors.

1762 | Honokiol DataSheet

Alternate Name/Synonyms: 2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol; HNK; Houpa

Appearance: White solid

Formulation: N/A

CAS Number: 35354-74-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₈O₂

Molecular Weight: 266.33

Cell-Permeable?: Yes

Purity: ≥97% by HPLC

Solubilities: DMSO (10 mg/ml) or EtOH

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A NF-kappaB modulator

MDL Number: MFCD00016674

PubChem CID: 72303

SMILES: C=CCC1=CC(=C(C=C1)O)C2=CC(=C(C=C2)O)CC=C

InChi: InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2

InChi Key: FVYXIJYOAGAUQK-UHFFFAOYSA-N