Hox-D8 polyclonal Antibody | BS5760

Hox-D8 polyclonal Antibody | BS5760 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB ICC

Application Range: WB: 1:500~1:1000 ICC: 1:50~1:200

Background: The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD8 (homeobox D8), also known as HOX4E, is a 290 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD8 functions as a sequence-specific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Hox-D8 polyclonal Antibody detects endogenous levels of Hox-D8 protein.

Molecular Weight: ~ 32 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Homeobox protein Hox-D8; Homeobox protein Hox-4E; Homeobox protein Hox-5.4; Name: HOXD8; HOX4E; Hox-5.4;

Immunogen: Synthetic peptide, corresponding to the 245-290 of Human Hox-D8.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: