HSCB Antibody | 16-347

HSCB Antibody | 16-347 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human HSCB (NP_741999.3) .

Research Area: Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: A-549

Positive Control 2: U-87MG

Positive Control 3: LO2

Positive Control 4: SGC-7901

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 27kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: DNAJC2HSC2JAC1, iron-sulfur cluster co-chaperone protein HscB, DnaJ (Hsp40) homolog, subfamily C, member 2HscB iron-sulfur cluster co-chaperone homolog, HscB mitochondrial iron-sulfur cluster co-chaperone, J-type co-chaperone HSC2epididymis secretory sperm binding protein, iron-sulfur cluster co-chaperone protein HscB, mitochondrial

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants.