hScrib | Protein LAP4 | AS06 155

hScrib | Protein LAP4 | AS06 155 | Gentaur UK, US & Europe Distribution

Immunogen: GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Serum

Format: Lyophilized

Tested Application: Western blot (WB)

Related Products: Secondary antibodies

Recommended Dilutions: 1 : 5 000 (WB)

Molecular weight: 175 kDa

Confirmed Reactivity: Human

Predicted Reactivity: Human

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: Reactivity showed on dilluted human cell culture extracts

Background: Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK. The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4

Reconstitution: For reconstitution add 100 µl of sterile water

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Other proteins

Research Area: Cell Biology