HSD3B7 Polyclonal Antibody | E-AB-11311

HSD3B7 Polyclonal Antibody | E-AB-11311 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 3 beta HSD VII, 3 beta hydroxy Delta(5) C27 steroid oxidoreductase, 3 beta hydroxysteroid dehydrogenase type 7, 3 beta hydroxysteroid dehydrogenase type VII, AI195443, BB098564, C(27) 3 beta HSD, Cca2, Cholest 5 ene 3 beta, 7 alpha diol 3 beta dehydrogenase, Confluent 3Y1 cell associated 2, Hydroxy delta 5 steroid dehydrogenase, 3 beta and steroid delta isomerase 7, OTTMUSP00000018894, OTTMUSP00000018895, OTTMUSP00000018897, PFIC4, SDR11E3

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction

Background: This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human HSD3B7

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A