Description
HSF1A is a cell-permeable activator of heat shock transcription factor 1 (HSF1). HSF1A protects cells from stress-induced apoptosis, binds TRiC subunits and inhibits TRiC activity without perturbation of ATP hydrolysis.
HSF1A is a cell-permeable activator of heat shock transcription factor 1 (HSF1). HSF1A protects cells from stress-induced apoptosis, binds TRiC subunits and inhibits TRiC activity without perturbation of ATP hydrolysis.
Alternate Name/Synonyms: 4-ethyl-N-(2-phenyl-5-thiophen-2-ylpyrazol-3-yl)benzenesulfonamide
Appearance: Off-white solid
Formulation: N/A
CAS Number: 1196723-93-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₁₉N₃O₂S₂
Molecular Weight: 409.52
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A cell-permeable activator of heat shock transcription factor 1 (HSF1)
MDL Number: N/A
PubChem CID: 44472508
SMILES: CCC1=CC=C(C=C1)S(=O)(=O)NC2=CC(=NN2C3=CC=CC=C3)C4=CC=CS4
InChi: InChI=1S/C21H19N3O2S2/c1-2-16-10-12-18(13-11-16)28(25,26)23-21-15-19(20-9-6-14-27-20)22-24(21)17-7-4-3-5-8-17/h3-15,23H,2H2,1H3
InChi Key: KJTITGSAONQVPY-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |